Company Overview
Batu Biologics is an immuno-oncology company focused on the development and commercialization of novel therapies that target the “Achilles Heel of Cancer”: the tumor blood vessels.
Angiogenesis, or the process of new blood vessel formation, is essential for the growth and metastasis of solid tumors. Tumors cannot grow larger than 1-2 millimeter in diameter without stimulating new blood vessels to feed them. Blocking this process has led to the development of multibillion-dollar blockbuster drugs such as Avastin ($7 billion 2015), Sunitinib ($1.1 billion 2016), and Revlimed ($3.2 billion 2011). Unfortunately these drugs target only one pathway of the angiogenesis process, and as a result tumor remissions are temporary, and in many cases not sustainable.
Batu Biologics’ flagship therapeutic, ValloVax™, is based on harnessing the immune system’s ability to selectively seek and destroy tumor-associated blood vessels, while sparing non-malignant blood vessels. In contrast to previous anti-angiogenic approaches, ValloVax™ stimulates the immune system to attack multiple pathways necessary for angiogenesis, thus having the potential for superior efficacy in the treatment of solid tumors. Batu Biologics sees the ValloVax™ platform as a powerful new immunotherapeutic approach to treating cancer that works synergistically with several already FDA approved drugs, and plans to develop the program clinically for multiple solid tumor indications.
Batu Biologics has recently received FDA regulatory clearance of our Investigational New Drug Application, enabling the Company to proceed with a Phase I study for patients with metastatic non small cell lung cancer.